Dr Conal Perrett

Presentations & publications

Presentations

  1. Perrett CM, Ilchyshyn A. Cutaneous Manifestations of Systemic Disease – Medical Grand Round, Walsgrave Hospital April 2002
  2. Perrett CM, McBride S. Generalised Pustular Psoriasis – Medical Grand Round, Royal Free Hospital October 2002
  3. Perrett CM, O’ Toole EA. Hypohidrotic Ectodermal Dysplasia – Royal Society of Medicine February 2003
  4. Perrett CM, Evans AV, Russell-Jones R. Tea Tree Oil Dermatitis associated with Linear IgA Disease. Poster presentation at the American Academy of Dermatology, San Francisco March 2003
  5. Perrett CM, CA Harwood, CM Proby, VL Brown, JM McGregor. Topical 5% imiquimod treatment for refractory cutaneous warts in immunosuppressed individuals. Poster presentation at the American Academy of Dermatology, Washington, February 2004
  6. Perrett CM, Cerio R, Khorshid M, McGregor JM. Actinic Prurigo associated with Cutaneous B cell Lymphoma. British Association of Dermatologists annual meeting, Belfast, July 2004
  7. Perrett CM, McGregor JM, Karran P, Harwood CA. Expression of DNA mismatch repair proteins hMLH-1 and hMSH-2 in cutaneous squamous cell carcinoma. British Association of Dermatologists annual meeting, Belfast, July 2004
  8. Perrett CM, O’ Donovan, Harwood CA, McGregor JM, Karran P. UVA-induced changes in DNA 6-TG and the development of organ transplant associated cutaneous malignancies. British Society for Investigative Dermatology, Cambridge, April 2005
  9. Perrett CM. Photodynamic therapy in dermatology. Multidisciplinary skin cancer symposium, Royal College of Pathologists, London, April 2005
  10. Perrett CM. Invited speaker, SCOR UK annual meeting, Royal Society of Medicine, November 2005
  11. Perrett CM. Azathioprine and UVA light generate mutagenic oxidative DNA damage, CRUK Quinquennial Review, Clare Hall Laboratories and Centre for Cutaneous Research, November 2005
  12. Perrett CM. Treatment of post-transplant pre-malignant skin disease: a randomised intra-patient comparative study of 5-FU cream and topical PDT. American Academy of Dermatology, San Francisco, March 2006
  13. Perrett CM. Skin Cancer in Organ Transplant Recipients. Invited lecture. Centre for Cutaneous Research, Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, May 2006
  14. Perrett CM. Topical PDT service at Barts and The London NHS Trust, June 2007
  15. Perrett CM. Sunscreen use in skin cancer patients on azathioprine. Grand Round. Whipps Cross University Hospital NHS Trust, April 2008
  16. Perrett CM. Azathioprine, UVA and Skin Cancer. Invited lecture. Chelsea and Westminster Hospital, January 2009
  17. Perrett CM. Azathioprine and skin cancer risk in patients with inflammatory bowel disease. Invited talk. Department of Gastroenterology, Barts and The London NHS Trust, July 2009
  18. T Maruthappu, W Rickaby, A Freeman, CM Perrett and C B Bunker. Trichoblastoma: A Rare Clinicopathological Entity Mimicking Basal Cell Carcinoma Presentation at American Academy of Dermatology, San Diego, March 2012.
  19. CM Perrett. PDT versus 5-fluorouracil. Invited lecture. Euro PDT Annual Meeting, Copenhagen, May 2012
  20. Maruthappu T, Perrett CM, Kumar VKA, Side LE. Isolated sebaceous skin tumours showing immunohistochemical loss of MSH2/MSH6 gene expression may not be associated with Lynch syndrome. Presentation at British Association of Dermatologists Annual Meeting, Birmingham, July 2012
  21. Wilmot M, Perrett C, Calonje E, Bunker CB. A case of acantholytic dermatosis localised to the male genitalia. Presentation at BAD Annual Meeting, Liverpool, July 2013.
  22. Thomas L, McGrath J, O’ Toole E, Perrett C. Inherited palmoplantar keratodermas-the heart of the matter. The Royal Society of Medicine, February 2014.
  23. Veitch D, Kravvas G, Perrett CM. Cirsoid aneurysms: A clinico-pathological reminder. Dermschool, BAD Annual Meeting Glasgow July 2014
  24. Veitch D, Kravvas G, Perrett CM. Cirsoid aneurysms: A clinico-pathological reminder. EADV Annual Meeting Amsterdam September 2014
  25. Chandrakumar A, Veitch, Proctor I, Hughes S, Perrett CM. Primary eccrine carcinoma treated with Mohs micrographic surgery and adjuvant radiotherapy. Poster presentation at World Skin Cancer Congress, Edinburgh September 2014
  26. Mehrtens S, Kulakov E, Veitch D, Perrett CM. Reed’s Syndrome: a clinicopathological reminder. Poster Presentation at American Academy of Dermatology (AAD), San Francisco March 2015
  27. Kulakov E, Siskou S, Perrett CM. Treatment of Basal Cell Carcinoma with Sequential Photodynamic Therapy and Imiquimod Cream may Improve Long Term Patient Outcomes. American Academy of Dermatology (AAD) San Francisco March 2015
  28. Rashed D, Shah D, Freeman A, Hopper C, & Perrett CM. Comparison of Mohs micrographic surgery with OCT. Laser Europe Conference, Brighton, UK, April 2015. (Awarded the Springer award for outstanding talk)
  29. G. Aberdein, D. Veitch and CM. Perrett. Mohs micrographic surgery for the treatment of superficial angiomyxoma. Poster Presentation BAD Annual Meeting Manchester, July 2015.
  30. G Kravvas, D Veitch, CM Perrett. A case of bullous skin disease presenting as odynophagia: a diagnostic challenge. Poster Presentation EADV Annual Meeting October 2015
  31. E Kulakov, S Siskou, CM Perrett. Treatment of Basal Cell Carcinoma with Sequential Photodynamic Therapy and Imiquimod Cream may Improve Long Term Patient Outcomes. Photodynamic Therapy (PDT) symposium, Royal Society of Medicine 30th November 2015
  32. M Noy, E Calonje, CM Perrett. A Case of Lymphoepithelial – like Carcinoma of the Skin (LELCS). Royal Society of Medicine, February 2016
  33. E. Kulakov, R Matin, C Proby, CM Perrett, F Ismail, J Marsden, C Harwood. Feasibility of a trial investigating the management of primary cutaneous squamous cell carcinoma (SCC): Conventional vs. Mohs Micrographic Surgery for high-risk SCC with or without Adjuvant Radiotherapy (COMMISSAR). Oral presentation BSDS Section, BAD Annual Meeting Birmingham, July 2016
  34. R Ramessur, CM Perrett. Sarcomatoid Carcinoma: A histological Janus. Royal Society of Medicine, February 2017
  35. G Kravvas, D Veitch, CM Perrett. Metastatic pleomorphic dermal sarcoma: case report of an uncommon skin cancer. American Academy of Dermatology Annual meeting Orlando March 2017.
  36. I Logan, K Vrobel, C Perrett. Pleomorphic Dermal Sarcoma: a tertiary referral center 5-year surgical experience. Oral presentation, BSDS Section BAD Annual Meeting Liverpool July 2017
  37. I Logan, K Vrobel, C Perrett. Pleomorphic Dermal Sarcoma: a tertiary referral center 5-year surgical experience. Oral presentation, BSDS Section BAD Annual Meeting Liverpool July 2017
  38. I Logan, K Vrobel, C Perrett. Pleomorphic Dermal Sarcoma: clinicopathological features and outcomes from a 5-year tertiary referral centre experience. Oral presentation, British Society for Dermatopathology Section, BAD Annual Meeting Liverpool July 2017
  39. C Angwin, E Ong, I Logan, C Perrett. Myofibroblastic Sarcoma: Clinicopathological features and experience from a Sarcoma Tertiary Referral Centre. American Academy of Dermatology (AAD) Annual Meeting, San Diego March 2018
  40. E Panagou, L Hussein, C Martyn-Simmons, C Perrett. A case of hidroacanthoma simplex in a cardiac transplant recipient. Poster presentation, BAD Annual Meeting, Liverpool July 2019.
  41. E Panou, W Bakkour, H Shaw, Perrett CM, M Ratnyska, C Bunker. Merkel Cell carcinoma in HIV. Poster presentation, BAD Annual Meeting Liverpool July 2019
  42. Effects of radiation exposure on dermal collagen: A multi modal approach. Maeva A, Bamber J, Seviaryna I, Hopper C, Perrett CM, Bozec L. Conference: Ultrasonic Imaging and Tomography. Volume:11319. DOI:1117/12.2549843. March 2020
  43. Maeva A, Strange A, Seviaryna I, Hopper C, Perrett CM, Trahair H, Devine O Akbar A. Age-related changes in collagen mechanical properties detected by high-resolution acoustic microscopy and AFM. Biomedical Applications in Molecular. Structural and Functional Imaging DOI – 10.1117/12.2587620. February 2021
  44. Y Alfallouji, Perrett CM, Bunker CB, Sidwell R. Encorafenib-induced eruptive naevi. St John’s Dermatological Society Clinical Meeting April 2021
  45. S Haddad, W Bakkour, CM Perrett, C Bunker. Accelerated photocarcinogenesis and multifocal SCC associated with voriconazole in HIV. St John’s Dermatological Society Clinical Meeting, June 2021

Invited Lectures

  • ‘PDT versus 5-fluorouracil.’ Euro PDT Annual Meeting, Copenhagen, May 2012
  • ‘Mohs surgery.’  London Cancer Educational Event Jan 2014
  • ‘Non Melanoma Skin Cancer.’  RCP Teach-in, Royal College of Physicians 5th May 2015
  • ‘Non Melanoma Skin Cancer an update and overview.’ Acute and General Medicine for the Physician Conference Royal College of Physicians 28th October 2015
  • ‘Non surgical Management of Basal Cell Carcinoma.’ 7th Annual Royal Marsden Head and Neck Conference, Royal College Physicians 13th November 2015

Book chapters

  1. Perrett CM, Harwood CA, McGregor JM, Karran P. Carcinogenic mechanisms related to immunosuppressive therapy. Cancer Treat Res. 2009;146:123-32
  2. Perrett CM, McGregor JM, Karran P, Harwood CA. Thiopurines and the sun: what should be done?  Clinical Dilemmas in Inflammatory Bowel Disease. Edited by Peter Irving et al. Wiley Blackwell 2011.

Publications

  1. Tea tree oil dermatitis associated with Linear IgA Disease. Perrett CM, Evans AV, Russell-Jones R.  Clin Exp Dermatol 2003;28:167-70
  2. Cyclosporin in childhood psoriasis. Perrett CM, Ilchyshyn A, Berth-Jones J. J Dermatol Treat 2003;14:107-112
  3. Gravitational Erythema. Perrett CM, Berth-Jones J, Dharma B. Br J Dermatol 2003;148 (6):1267.
  4. Etanercept-induced Systemic Lupus Erythematosus. Swale VJ, Perrett CM, Denton CP, Black CM, Rustin MHA. Clin Exp Dermatol. 2003 Nov;28:604-7
  5. Teicoplanin Induced Drug Hypersensitivity Syndrome. Perrett CM, McBride S. BMJ 2004;328(7451):1292
  6. Topical 5% imiquimod treatment for refractory cutaneous warts in immunosuppressed individuals. Perrett CM, CA Harwood, CM Proby, VL Brown, JM McGregor. J Am Acad Dermatol 2004 (part 2); 50: Number 3
  7. Expression of DNA mismatch repair proteins hMLH-1 and hMSH-2 in cutaneous squamous cell carcinoma. Perrett CM, McGregor JM, Cerio R, Karran P, Harwood CA. Br J Dermatol 2004;151(Suppl 68):81-90
  8. Actinic prurigo associated with cutaneous B cell lymphoma. Perrett CM, Cerio R, Khorshid M, McGregor JM. Br J Dermatol 2004;151(Supp 68):106
  9. Topical 5% imiquimod treatment for refractory cutaneous warts in immunosuppressed individuals. Harwood CA, Perrett CM,  Proby CM, Brown VL, McGregor JM. Br J Dermatol 2005 Jan;152(1):122-9
  10. Atypical fibroxanthoma in a renal transplant recipient. Perrett CM, Cerio R, Harwood C.  Histopathology 2005;47(3):326-7
  11. Primary cutaneous B-cell lymphoma associated with actinic prurigo. Perrett CM, Cerio R, Khorshid M, McGregor JM. Br J Dermatol. 2005 Jul;153(1):186-9
  12. Azathioprine and UVA light generate mutagenic oxidative DNA damage. O’Donovan P, Perrett CM, Zhang X, Montaner B, Xu YZ, Harwood CA, McGregor JM, Walker SL, Hanaoka F, Karran P. Science. 2005 Sep 16;309(5742):1871-4
  13. Treatment of basal cell carcinoma with topical methylaminolaevulinate photodynamic therapy in an organ-transplant recipient. Perrett CM, Tan SK, Cerio R, Goldsmith PC, McGregor JM, Proby CM, Harwood CA. Clin Exp Dermatol. 2006 Jan;31(1):146-7
  14. Topical photodynamic therapy with methyl aminolevulinate to treat sebaceous hyperplasia in an organ transplant recipient. Perrett CM, J McGregor, Barlow R, P Karran, C Proby, CA Harwood. Arch Dermatol. 2006 Jun;142(6):781-2
  15. Treatment of post-transplant premalignant skin disease: a randomized intrapatient comparative study of 5-fluorouracil cream and topical photodynamic therapy. Perrett CM, McGregor JM, Proby CM, Karran P, Warwick J, Leigh IM, Harwood CA. Br J Dermatol. 2007 Feb;156(2):320-8
  16. Novel DNA lesions generated by the interaction between thiopurines and UVA light. Zhang X, Jeffs G, Ren X, O’ Donovan P, Montaner B, Perrett CM, Karran P, Xu YZ. DNA Repair (Amst). 2007 Mar 1;6(3):344-54
  17. Vulval intraepithelial neoplasia and periungual Bowen’s disease concordant for mucosal (HPV-34) and epidermodysplasia verruciformis (HPV-21) human papillomavirus types. Ekeowa – Anderson AL, Harwood CA, Perrett CM, Sahota A, Annan H, Ran H, Leigh IM, Gibbon KL. Clin Exp Dermatol. 2007 May;32(3):304-7
  18. Reactive oxygen-mediated damage to a human DNA replication and repair protein.  Montaner B, O’Donovan P, Reelfs O, Perrett CM, Zhang X, Xu, YZ, Ren X, Macpherson P, Frith D, Karran P. EMBO Rep. 2007 Nov;8(11):1074-9
  19. Azathioprine treatment photosensitises human skin to ultraviolet-A radiation. Perrett CM, Walker SL, O’ Donovan P, Warwick J, Harwood CA, Karran P, McGregor JM. Br J Dermatol 2008 Jul;159(1):198-204
  20. Dermoscopy of   trichostasis spinulosa. Pozo L, Bowling J, Perrett CM, Bull R, Diaz-Cano S. Arch Dermatol. 2008 Aug;144(8):1088
  21. PTCH mutations in basal cell carcinomas from azathioprine-treated organ transplant recipients. Harwood CA, Attard NR, O’Donovan P, Chambers P, Perrett CM, Proby CM, McGregor JM, Karran P. Br J Cancer 2008 Oct 21;99(8):1276-84
  22. Expression of DNA mismatch repair proteins and MSH2 polymorphisms in nonmelanoma skin cancers of organ transplant recipients. Perrett CM, McGregor JM, Cerio R, Karran P, Harwood CA.  Br J Dermatol. 2010;162(4):732-42
  23. Atypical Fibroxanthoma in an HIV infected individual. Perrett CM, Macedo C, Francis N, Ion L, Bunker CB.  J Cutan Pathol 2011;38(4):357-9
  24. Key questions: Skin Cancer. CM Perrett. Pulse. October 2012
  25. A crusted lesion on the penis. Wilmot MC, Perrett CM, Calonje E, Weir, Bunker CB. Clin Exp Dermatol. 2014;39(2): 238-9
  26. Treatment of multiple periocular eccrine hidrocystoma: is botulinum toxin or electrocautery more effective? Meys R, Perrett CM.  Clin Exp Dermatol. 2015 Jan;40(1): 101- 3
  27. Chandrakumar A, Veitch D, Proctor I, Hughes S, Perrett CM. Primary eccrine carcinoma treated with Mohs micrographic surgery and adjuvant radiotherapy. Clin Exp Dermatol. 2015 Mar; 40(2): 204-5
  28. Cirsoid aneurysm: a clinicopathological reminder. Veitch D, Kravvas G, Perrett CM. Clin Exp Dermatol. 2015 Oct;40(7):822-3. doi: 10.1111/ced.12611. Epub 2015 Mar 1
  29. A Case of Hereditary Leiomyomatosis and Renal Cell Carcinoma. Mehrtens S, Veitch D, Kulakov E, Perrett CM. Case Rep Dermatol Med. 2016;2016:3793986. doi: 10.1155/2016/3793986. Epub 2016 Apr 7. PMID: 27144040
  30.  A Case of Bullous Skin Disease Presenting with Odynophagia: A Diagnostic Challenge. Kravvas G, Veitch D, Perrett CM. Case Rep Dermatol Med. 2016;2016:2839104. doi: 10.1155/2016/2839104. Epub 2016 Mar 14. PMID: 2706627
  31. Mohs Micrographic Surgery for the Treatment of Superficial Angiomyxomas      Aberdein G, Veitch D, Perrett C. Dermatol Surg. 2016 Aug;42(8):1014-6.
  32. Lymphoepithelioma-Like Carcinoma of the Skin- A Rare Tumor Treated by Slow  Mohs Micrographic Surgery. Tzanidakis K, Noy ML, Calonje E, Perrett CM. Dermatol Surg. 2017 Apr;43(4):595-597.
  33. Rapid ex vivo examination of Mohs specimens using optical coherence tomography. Rashed D, Shah D, Freeman A, Cook RJ, Hopper C, Perrett CM. Photodiagnosis and Photodyn Therapy. 2017 Sep;19:243-248. Doi:10.1016/j.pdt.2017.06.0006. Epub 2017 Jun 12
  34. Multicentric visceral epithelioid hemangioendothelioma, with extremity dermal deposits, unusual late recurrence on the nasal bridge and TFE3 gene rearrangement. Thway K, Mentzel T, Perrett CM, Calonje E. Hum Pathol 2017Aug 27.pii:S0046-8177(17)30302-7.doi:10.1016/j.humpath.2017.08.020 (Epub ahead of print)
  35. Inherited palmoplantar keratodermas: the heart of the matter. Thomas  LJ, O’ Toole E, McGrath J, Freeman A, Perrett CM. Clin Exp Dermatol. 2017 Sep 22 (Epub ahead of print)
  36. Metastatic Pleomorphic Dermal Sarcoma. Kravvas G, Logan I, Perrett CM. Astaric pleonais Brasileiros de Dermatologia. 2018 Mar;93(2):307-308
  37. Panagou E, Ellery P, Martyn-Simmons C, Perrett C. A case of hidroacanthoma simplex in a cardiac transplant recipient. Transplantation. 2019 Sep 30. doi: 10.1097/TP.0000000000002988. [Epub ahead of print]
  38. Logan IT, Zaman S, Hussein L, Perrett CM. Combination therapy of ipilimumab and Nivolumab-associated Toxic Epidermal Necrolysis (TEN) in a patient with Metastatic Melanoma: A Case Report and Literature Review. J Immunother. 2019 Oct 23. doi: 10.1097/CJI.0000000000000302. [Epub ahead of print]
  39. Logan I, Kulakov E, Calnan M, Perrett CM. Sequential treatment of Superficial Basal Cell Carcinomas with topical methyl aminolevulinate photodynamic therapy and imiquimod 5% cream: a retrospective study of clinical and cosmetic outcomes. Dermatol Surg. 2020 Jan 31. doi: 10.1097/DSS.0000000000002306. [Epub ahead of print]
  40. Hussein L, Perrett C. Treatment of sebaceous gland hyperplasia: a review of the literature. J Dermatolog Treat. 2020 Feb 3:1-33. doi:10.1080/09546634.2020.1720582. [Epub ahead of print]
  41. Gollins CE, Shah A, Sinha K, Khan S, Paul N, Meeajun B, Abbott RA, Blasdale C, Cooper H, Harwood CA, Ismail F, Lear JT, Mackintosh L, McCormack S, Perrett CM, Proby CM, Durack A, Patalay R, Matin RN. Feasibility of a trial to evaluate nicotinamide for chemoprevention of skin cancers in organ transplant recipients in the UK. Br J Dermatol. 2020 Mar 2. doi: 10.1111/bjd.18982. [Epub ahead of print]
  42. Logan IT, Shaw H, Perrett CM. Clinical management of advanced skin cancer. Dermatology in practice 2020; 26(2): 4–8
  43. Logan IT, Vroobel KM, le Grange F, Perrett CM. Pleomorphic dermal sarcoma: Clinicopathological features and outcomes from a 5-year tertiary referral centre experience. Cancer Rep (Hoboken). 2021 Nov 11:e1583. doi: 10.1002/cnr2.1583. Online ahead of print.PMID: 34766474

Click here to access all publications

Abstracts

  • C Angwin, E Ong, I Logan, C Perrett. Myofibroblastic Sarcoma: Clinicopathological features and experience from a Sarcoma Tertiary Referral Centre. American Academy of Dermatology (AAD) Annual Meeting, San Diego March 2018
  • I Logan, K Vrobel, C Perrett. Pleomorphic Dermal Sarcoma: a tertiary referral center 5-year surgical experience. Br J Dermatol 2017;177(Suppl 1): 104-127
  • I Logan, K Vrobel, C Perrett. Pleomorphic Dermal Sarcoma: clinicopathological features and outcomes from a 5-year tertiary referral centre experience. Br J Dermatol 2017;177(Suppl 1): 128-139
  • Attard N, LI F, Gueranger  Q, Harwood CA, McGregor JM, Perrett CM, Karran P. DNA repair and azathioprine immunosuppression. Br J Dermatol 2012; 167 (Suppl): 114-126.
  • Maruthappu T, Side LE, Freeman A, Perrett CM. Sebaceoma in an immunosuppressed organ transplant recipient. Br J Dermatol 2012; 167 (Suppl 1): 114-126.
  • Maruthappu T, Perrett CM, Kumar VKA, Side LE. Isolated sebaceous skin tumours showing immunohistochemical loss